Product ID:TETRODOTOXIN, T8024
MSDS Date:12/22/1988
FSC:6810
NIIN:00N021689
MSDS Number: BLWSV

Emergency Phone: 314-771-5765

Info Phone: 800-325-8070

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

IMINO-(TETRODOTOXIN)

CAS: 4368-28-9

RTECS: 9999999ZZ

LD50 LC50 Mixture:LD50:ORAL(RAT)334 UG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:MAY BE HARMFUL IF INHALED, SWALLOWED,
ABSORBED THROUGH SKIN. TETRODOTOXIN IS AMONG THE MOST TOXIC
SUBSTANCES KNOWN TO MAN. DEATH CAN OCCUR WITHIN 30 MINUTES. IT IS
EXTREMELY DANGEROUS BY INGESTION, IN HALATION AND SKIN ABSORPTION,
OR IF IT ENTERS THE BLOODSTREAM IN ANY MANNER. SYMPTOMS OF
POSIONING(SEE EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT.
Effects of Overexposure:HLTH HAZ: WHICH INCLUDE NUMBNESS, TINGLING OF
LIPS AND INNER MOUTH SURFACES, WEAKNESS, PARALYSIS OF LIMBS AND
CHEST MUSCLES, AND DROP IN BLOOD PRESSURE HAVE BEEN REPORTED WITHIN
AS LITTLE AS 10 MIN AF TER EXPOSURE.
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:IN CASE OF EXPOS, OBTAIN MED ATTN IMMED. INGEST:WASH OUT
MOUTH W/H2O PROVIDED PERSON IS CONSCIOUS. CALL PHYS. SKIN: FLUSH
W/COPIOUS AMT OF H2O FOR @ LST 15 MIN. REMOVE CONTAMD CLTHG/SHOES &
CALL PHYS. INHAL:REMOVE TO FRESH AIR. IF BREATHING BECOMES
DIFFICULT, CALL PHYS. EYES: FLUSH WITH COPIOUS AMOUNTS OF WATER FOR
AT LEAST 15 MIN. ASSURE ADEQ FLUSH BY SEPARATING LIDS W/FINGERS.
CALL PHYS.

Extinguishing Media:CARBON DIOXIDE, DRY CHEMICAL POWDER, ALCOHOL OR
POLYMER FOAM.
Fire Fighting Procedures:WEAR NIOSH/MSHA APPROVED SCBA AND FULL
PROTECTIVE EQUIPMENT TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:NONE SPECIFIED BY MANUFACTURER.

Spill Release Procedures:WEAR SCBA/RUB BOOTS/HEAVY RUB GLOVES. ABSORB
ON SAND ON VERMICULITE/PLACE IN CLSD CONTR FOR DISP. TETRODOTOXIN
CAN BE DETOXIFIED BY PRLNG BOILING, OR BY TREAT W/STRONGLY
ACIDIC/ALKALINE SOLN. VENT ARE A & WASH SPILL SITE AFTER MATL
PICKUP IS COMPLETE.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:HNDL IN CLSD SYS. VERY TOX BY INHAL,
IN CONT W/SKIN & IF SWALLOWED. IF YOU FEEL UNWELL, SEEM MED
ADVICE(SHOW LABEL WHERE POSS). DO NOT BREATHE DUST.
Other Precautions:READ ENCLSD SAFTY DATA SHEET BEFORE OPEN.
TETRODOTOXIN SHOULD BE STORED IN TIGHTLY CLSD METAL CAN @ 0-5C.
PHYS SHOULD BE NOTIFIED PRIOR TO WORK W/PROD, IN ORDER TO BE
PREPARED IN EVENT OF EMER. SHOULD ACCIDENTAL EXPOS OCCUR, CONT
(SUPDAT)

Respiratory Protection:NIOSH/MSHA APPROVED SCBA SHOULD BE WORN.
Ventilation:NONE SPECIFIED BY MANUFACTURER.
Protective Gloves:COMPATIBLE CHEMICAL RESISTANT GLOVES.
Eye Protection:CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:WEAR DISPOSABLE CLOTHING, LONG-SLEEVE
COVERALLS WITH TIGHT COLLAR & CUFFS & SHOE COVERS.
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health
OTHER PREC: PHYS AT ONCE & INFORM HIM THAT YOU HAVE BEEN EXPOSED TO
TETRODOTOXIN. IF NUMBNESS OCCURS, START ARTF RESP & CONTINUE UNTIL
MED HELP ARRIVES.

HCC:F3
Melt/Freeze Pt:M.P/F.P Text:392F,200C
Solubility in Water:SLIGHTLY SOLUBLE
Appearance and Odor:SOLID

Stability Indicator/Materials to Avoid:YES
NONE SPECIFIED BY MANUFACTURER.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:NONE SPECIFIED BY MANUFACTURER.

Waste Disposal Methods:DISSOLVE OR MIX MATERIAL WIHT COMBUSTIBLE
SOLVENT AND BURN IN CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER OR SCRUBBER. OBSERVE ALL FEDERAL, STATE, AND LOCAL
LAWS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.